Front Cover Picture: Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry – Preparation and Synthetic Application of 1‐Azoniabicyclo[n.1.0]alkanes (Adv. Synth. Catal. 22/2016). Issue 22 (10th October 2016)

• Record Type: Journal Article
• Authors: Dolfen, Jeroen; Yadav, Nagendra Nath; De Kimpe, Norbert; D'hooghe, Matthias; Ha, Hyun‐Joon
• Is Part Of: Advanced synthesis & catalysis. Volume 358:Issue 22(2016)
• Page Start: 3483
• Page End: 3483
• Publication Date: 2016-10-10
• Subjects: azaheterocyclic chemistry -- bicyclic aziridinium ions -- regioselectivity -- ring expansion -- stereoselectivity; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201601081
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract : The front cover picture illustrates the use of 1‐azoniabicyclo[n.1.0]alkane scaffolds (bicyclic aziridinium ions), which have emerged as versatile synthetic intermediates for the construction of a broad variety of nitrogen‐containing heterocycles. The corresponding review article provides a comprehensive survey of all pathways leading to the generation of 1‐azoniabicyclo[n.1.0]alkanes, as well as a discussion on their subsequent ring expansions to relevant azaheterocycles, governed by ring size, substitution pattern, and/or the nature of the applied nucleophiles. Details can be found in the review on pages 3485–3511 (J. Dolfen, N. N. Yadav, N. De Kimpe, M. D'hooghe, H.‐J. Ha, Adv. Synth. Catal .2016, 358, 3485–3511; DOI:10.1002/adsc.201600750) .