Caveolin-1 polymorphisms in patients with severe obstructive sleep apnea. (2nd January 2017)

• Record Type: Journal Article
• Authors: Asker, Selvi; Taspinar, Mehmet; Koyun, Hasan; Ozbay, Bulent; Arisoy, Ahmet
• Is Part Of: Biomarkers. Volume 22:Number 1(2017)
• Page Start: 77
• Page End: 80
• Publication Date: 2017-01-02
• Subjects: G14713A -- genotype -- polymorphic variant -- T29107A; Biochemical markers -- Periodicals; 610.28
• DOI: 10.1080/1354750X.2016.1204007
• Languages: English
• ISSNs: 1354-750X

Abstract

Abstract: Objective: To investigate the associations of G14713A and T29107A polymorphic variants of Caveolin-1 with severe obstructive sleep apnea (OSA). Materials and methods: This study was performed on 86 severe OSA patients and 86 controls. Genotyping was performed to investigate the association of G14713A and T29107A polymorphisms of Caveolin-1 with severe OSA. Results: The distribution of genotypes of T29107A was significantly different between controls and OSA patients with a higher proportion of TT carriers in the OSA group. Conclusion: T29107A-specific genotype of Caveolin-1 may be linked with severe OSA pathogenesis.