Exploring vector-borne infection ecology in multi-host communities: A case study of West Nile virus. (21st February 2017)

• Record Type: Journal Article
• Authors: Marini, Giovanni; Rosá, Roberto; Pugliese, Andrea; Heesterbeek, Hans
• Is Part Of: Journal of theoretical biology. Volume 415(2017)
• Page Start: 58
• Page End: 69
• Publication Date: 2017-02-21
• Subjects: Epidemiology -- Mosquito-borne infection -- Competition -- Vector feeding preference; Biology -- Periodicals; Biological Science Disciplines -- Periodicals; Biology -- Periodicals; Biologie -- Périodiques; Theoretische biologie; Biology; Periodicals; 571.05
• DOI: 10.1016/j.jtbi.2016.12.009
• Languages: English
• ISSNs: 0022-5193

Abstract

Abstract: In this study, we develop a model to investigate how ecological factors might affect the dynamics of a vector-borne pathogen in a population composed by different hosts which interact with each other. Specifically, we consider the case when different host species compete with each other, as they share the same habitat, and the vector might have different feeding preference, which can also be time dependent. As a prototypical example, we apply our model to study the invasion and spread, during a typical season, of West Nile virus in an ecosystem composed of two competent avian host species and possibly of dead-end host species. We found that competition and vector feeding preferences can profoundly influence pathogen invasion, influencing its probability to start an epidemic, and influencing transmission rates. Finally, when considering time-dependent feeding preferences, as observed in the field, we noted that the virus circulation could be amplified and that the timing of epidemic peaks could be changed. Our work highlights that ecological interactions between hosts can have a profound influence on the dynamics of the pathogen and that, when modeling vector-borne infections, vector feeding behavior should, for this reason, be carefully evaluated. Abstract : Highlights: We develop a vector-borne infection model in a multi-host-vector system. We explore the effect of host competition and changing vector feeding preferences. Competition strongly affects pathogen invasion and spread. Vector feeding preferences influence epidemic seasonal pattern.