Surface properties of polyene glycol phospholipid monolayers. (January 2017)

• Record Type: Journal Article
• Authors: Hianik, Tibor; Øpstad, Christer L.; Šandorová, Jana; Garaiová, Zuzana; Partali, Vassilia; Sliwka, Hans-Richard
• Is Part Of: Chemistry and physics of lipids. Volume 202(2017)
• Page Start: 13
• Page End: 20
• Publication Date: 2017-01
• Subjects: Polyenes -- Carotenoids -- Diol phospholipids -- Langmuir monolayers -- Surface pressure -- Dipole potential; Lipids -- Periodicals; Lipids -- Periodicals; Lipides -- Périodiques; Lipids; Periodicals; Electronic journals; 547.77
• DOI: 10.1016/j.chemphyslip.2016.11.007
• Languages: English
• ISSNs: 0009-3084

Abstract

Graphical abstract: Highlights: Conjugated polyene ethylene glycol lipids form monolayers at water subphase. Compressibility modulus of monolayers depends on the glycol lipids mole fraction. DPPC – glycol lipids complexes occur in mixed monolayers. Dipole potential indicate various orientation of the glycol lipids in the monolayer. Abstract: We studied the surface properties of monolayers composed of polyunsaturated conjugated ethylene glycol phospholipids (carotenoid lipids), compared the data with monolayers of dipalmitoylphosphatidylcholine (DPPC) to which carotenoids were added and evaluated the impact of the unsaturated glycol lipids on monolayers with the glycerolipid DPPC. The carotenoid based glycol lipids formed monolayers at the air/water interface. Using the Langmuir method we obtained series of pressure-area ( π-A ) isotherms and determined the limiting area A per molecule of three glycol lipids, C30:9-C0 A = 42.6 ± 1.4 Å 2, C30:9-C2 A = 76.1 ± 2.5 Ǻ 2 and C30:9-C12 A = 354.0 ± 12.0 Å 2 and their mixtures with DPPC at various mole fraction X . C30:9-C0 and C30:9-C2 did not affect significantly the shape of the isotherm, but caused their slight shift toward a lower and larger molecular area, respectively. C30:9-C12 at mole fractions X > 0.02 affected the shape of isotherm. The compressibility modulus Cs −1 of monolayers depended on the surface pressure. Cs −1 value was substantially higher for DPPC monolayers in comparison with those of pure glycol lipids. At low surface pressure π = 5–10 mN/m and low mole fractions X < 0.02 the glycol lipids formed complexes with DPPC; at higher surface pressure the separation of pure components took place. The dipole potential of the monolayers composed of cationic glycol lipids C30:9-C2 and C30:9-C12 was higher in comparison with those of zwitterionic DPPC and C30:9-C0 . This may be connected with various contributions of dipole moments of the molecules and their orientation in the monolayer.