Mallory Weiss syndrome is not associated with hiatal hernia: a matched case–control study. (3rd April 2017)

• Record Type: Journal Article
• Authors: Corral, Juan E.; Keihanian, Tara; Kröner, Paul T.; Dauer, Ryan; Lukens, Frank J.; Sussman, Daniel A.
• Is Part Of: Scandinavian journal of gastroenterology. Volume 52:Number 4(2017)
• Page Start: 462
• Page End: 464
• Publication Date: 2017-04-03
• Subjects: Mallory Weiss -- gastrointestinal bleeding -- hiatal hernia -- esophagus; Gastroenterology -- Periodicals; Digestive organs -- Diseases -- Periodicals; 616.33
• DOI: 10.1080/00365521.2016.1267793
• Languages: English
• ISSNs: 0036-5521

Abstract

Abstract: Background/objective: Hiatal hernia is considered to be a predisposing factor to develop Mallory-Weiss Syndrome (MWS). No large case–control studies verifying this hypothesis have been conducted. Methods: We reviewed all esophagogastroduodenoscopies with findings of MWS ( n = 2342) in a national database and compared with age and gender-matched controls ( n = 9368). Demographics, endoscopic characteristics and presence of a hiatal hernia were compared between both groups. Average age was 56.7 ± 18.6 years, and 72.4% were male. Results: Hiatal hernia was more common in controls, and no significant difference was seen in a multivariate analysis. Conclusion: Dynamic changes inducing mucosal tension are more relevant determinants to develop MWS than gastro-esophageal junction location alone.