Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application. Issue 6 (3rd January 2017)

• Record Type: Journal Article
• Authors: Takano, Yoko; Hanaoka, Kenjiro; Shimamoto, Kazuhito; Miyamoto, Ryo; Komatsu, Toru; Ueno, Tasuku; Terai, Takuya; Kimura, Hideo; Nagano, Tetsuo; Urano, Yasuteru
• Is Part Of: Chemical communications. Volume 53:Issue 6(2017)
• Page Start: 1064
• Page End: 1067
• Publication Date: 2017-01-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc08372b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : We developed a reversible fluorescent probe for sulfane sulfur. This probe enabled us to monitor concentration changes of sulfane sulfur. Abstract : We report a reversible off/on fluorescent probe for monitoring concentration changes of sulfane sulfur by utilizing the unique ability of sulfane sulfur to bind reversibly to other sulfur atoms and the intramolecular spirocyclization reaction of xanthene dyes. It reversibly visualized sulfane sulfur in living A549 cells and primary-cultured hippocampal astrocytes.