Photocatalytic C−C Bond Cleavage and Amination of Cycloalkanols by Cerium(III) Chloride Complex. Issue 49 (11th November 2016)

• Record Type: Journal Article
• Authors: Guo, Jing‐Jing; Hu, Anhua; Chen, Yilin; Sun, Jianfeng; Tang, Haoming; Zuo, Zhiwei
• Is Part Of: Angewandte Chemie international edition. Volume 55:Issue 49(2016)
• Page Start: 15319
• Page End: 15322
• Publication Date: 2016-11-11
• Subjects: alcohols -- amination -- C−C bond cleavage -- cerium -- photochemistry; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201609035
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: A general strategy for the cleavage and amination of C−C bonds of cycloalkanols has been achieved through visible‐light‐induced photoredox catalysis utilizing a cerium(III) chloride complex. This operationally simple methodology has been successfully applied to a wide array of unstrained cyclic alcohols, and represents the first example of catalytic C−C bond cleavage and functionalization of unstrained secondary cycloalkanols. Abstract : Breaking (D)BAD : A general strategy for the cleavage and amination of C−C bonds of cycloalkanols has been achieved through visible‐light‐induced photoredox catalysis utilizing a cerium(III) chloride complex. This method represents the first example of catalytic C−C bond cleavage and functionalization of unstrained secondary cycloalkanols. DBAD=di‐ tert ‐butyl azodicarboxylate, Boc= tert ‐butoxycarbonyl.