Rhodium‐Catalyzed Diastereoselective Cyclization of Allenyl‐Sulfonylcarbamates: A Stereodivergent Approach to 1, 3‐Aminoalcohol Derivatives. (15th November 2016)
- Record Type:
- Journal Article
- Title:
- Rhodium‐Catalyzed Diastereoselective Cyclization of Allenyl‐Sulfonylcarbamates: A Stereodivergent Approach to 1, 3‐Aminoalcohol Derivatives. (15th November 2016)
- Main Title:
- Rhodium‐Catalyzed Diastereoselective Cyclization of Allenyl‐Sulfonylcarbamates: A Stereodivergent Approach to 1, 3‐Aminoalcohol Derivatives
- Authors:
- Spreider, Pierre A.
Haydl, Alexander M.
Heinrich, Marc
Breit, Bernhard - Abstract:
- Abstract: A diastereoselective and stereodivergent rhodium‐catalyzed intramolecular coupling of sulfonylcarbamates with terminal allenes is described and it provides selective access to 1, 3‐aminoalcohol derivatives, scaffolds found in bioactive compounds. The reaction is compatible with a large range of different functional groups, thus furnishing products with high diastereoselectivities and yields. Moreover, multigram scale reactions, as well as the application of suitable product transformations were demonstrated.
- Is Part Of:
- Angewandte Chemie. Volume 128:Number 50(2016)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 128:Number 50(2016)
- Issue Display:
- Volume 128, Issue 50 (2016)
- Year:
- 2016
- Volume:
- 128
- Issue:
- 50
- Issue Sort Value:
- 2016-0128-0050-0000
- Page Start:
- 15798
- Page End:
- 15802
- Publication Date:
- 2016-11-15
- Subjects:
- Alkohole -- Allene -- Allylverbindungen -- Rhodium -- Synthesemethoden
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201609366 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 1183.xml