Amperometric biosensor based on electrochemically reduced graphene oxide/poly(m-dihydroxybenzene) composites for glucose determination. (2nd January 2017)

• Record Type: Journal Article
• Authors: Li, S.; Xiong, J.-X.; Chen, C.-X.; Chu, F.-Q.; Kong, Y.; Deng, L.-H.
• Is Part Of: Materials technology. Volume 32:Number 1(2017)
• Page Start: 1
• Page End: 6
• Publication Date: 2017-01-02
• Subjects: Reduced graphene oxide -- Poly(m-dihydroxybenzene) -- Composites -- Amperometric sensor -- Glucose determination; Materials -- Periodicals; Materials science -- Periodicals; Materials -- Technological innovations -- Periodicals; 620.1105
• DOI: 10.1080/10667857.2015.1109162
• Languages: English
• ISSNs: 1066-7857

Abstract

Abstract : A novel amperometric biosensor was designed via immobilization of glucose oxidase (GOD) into the composite films of electrochemically reduced graphene oxide (RGO) and poly( m -dihydroxybenzene) (P m DB). P m DB was first electrodeposited onto the surface of a glassy carbon electrode by electrochemical polymerization of m -dihydroxybenzene in the presence of graphene oxide (GO). Next, the obtained GO/P m DB composites were electrochemically reduced to RGO/P m DB at a negative potential. The RGO/P m DB composites were characterized by scanning electron microscopy (SEM), cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The RGO/P m DB composites exhibited high electrocatalytic activity towards the oxidation of hydrogen peroxide (H2 O2 ), and therefore, they were used for sensitive glucose determination by immobilizing GOD within the composite films. The as-prepared glucose biosensor exhibited a linear response ranging from 0.5 to 15 mM, a low detection limit of 0.023 mM ( S / N = 3). Also, the RGO- /P m DB-based glucose sensor displayed excellent selectivity as well as good reproducibility and stability.