A Systematic Review and Meta-analysis on the Efficacy of Intravesical Therapy for Bladder Pain Syndrome/Interstitial Cystitis. Issue 11 (November 2016)

• Record Type: Journal Article
• Authors: Barua, Jayanta M.; Arance, Ignacio; Angulo, Javier C.; Riedl, Claus R.
• Is Part Of: Obstetrical & gynecological survey. Volume 71:Issue 11(2016)
• Publication Date: 2016-11
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/OGX.0000000000000380
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from Int Urogynecol J 2016;27:1137–1147) Although the precise pathophysiology of bladder pain syndrome/interstitial cystitis (BPS/IC) is unclear, the underlying mechanism appears related to a defect in the urine-tissue barrier (the bladder's protective mucous lining of glycosaminoglycans [GAG]). This defect has been documented in a subset of BPS/IC patients, and a favorable response to GAG-restoring agents has been reported.