Actinobacillus ureae: an unusual cause of tree-in-bud pattern in a case of pneumonia on lung computed tomographic scan—first clinical case report and review of the literature from India. (November 2016)

• Record Type: Journal Article
• Authors: Dawar, R.; Nagarjuna, D.; Gupta, R.; Ghonge, N.P.; Sardana, R.
• Is Part Of: New microbes and new infections. Volume 14(2016)
• Page Start: 69
• Page End: 72
• Publication Date: 2016-11
• Subjects: 16sRNA sequencing -- Actinobacillus -- Bronchial asthma -- MALDI-TOF -- Pneumonia -- Tree in bud appearance; Medical microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; Microbiology -- Periodicals; Communicable Diseases -- Periodicals; Infection -- Periodicals; 616.9041
• DOI: 10.1016/j.nmni.2016.09.005
• Languages: English
• ISSNs: 2052-2975

Abstract

Abstract: A 62-year-old man with asthma sought care for intermittent fever, cough with expectoration, breathlessness and orthopnoea with grunting. Computed tomography revealed clusters of centrilobular nodules on both sides with a tree-in-bud appearance and mild diffuse bronchial wall thickening. Sputum sample grew pure colonies of Actinobacillus ureae which was confirmed by MALDI-TOF and 16SrRNA gene sequencing. A. ureae may be an additional bacteriologic causative agent of the tree-in-bud pattern on computed tomographic scan.