Cobalt catalysed, copper assisted C(sp2)–P cross coupling. (10th October 2016)

• Record Type: Journal Article
• Authors: Ghosh, Tubai; Maity, Pintu; Kundu, Debasish; Ranu, Brindaban C.
• Is Part Of: New journal of chemistry. Volume 40:Number 11(2016:Nov.)
• Page Start: 9556
• Page End: 9564
• Publication Date: 2016-10-10
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c6nj02247b
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : An efficient C(sp 2 )–P cross coupling has been achieved using a Co/Cu catalytic system for access to vinyl and aryl phosphonates. Abstract : An efficient protocol for the cross coupling of styrenyl/aryl halides and H-phosphinate has been developed using a unique Co/Cu catalytic system in the absence of any additional ligand for the first time. A library of diversely functionalised styrenyl/aryl phosphonates has been synthesized using this procedure. The advantages offered using this procedure are operational simplicity, the use of inexpensive and relatively benign metals as a catalyst, wide tolerance to functionality including electron withdrawing and releasing substituents, excellent stereoselectivity and high yields. The mechanism has also been established. The unique feature of this Co/Cu system is that, it primarily involves Co in the catalytic cycle and Cu in the transmetalation process.