A novel rosamine-based fluorescent probe for bisulfite in aqueous solution. Issue 106 (1st November 2016)

• Record Type: Journal Article
• Authors: Zhang, Di; Wenya, Liu; Chen, Keke; Cheng, Junye; Zhao, Yufen; Ye, Yong
• Is Part Of: RSC advances. Volume 6:Issue 106(2016)
• Page Start: 103905
• Page End: 103909
• Publication Date: 2016-11-01
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra24667b
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A new rosamine-based fluorescent chemodosimeter has been developed for highly sensitive and selective detection of bisulfite in aqueous solution. Abstract : A new rosamine-based fluorescent probe (RosCHO ) for bisulfite was obtained by one pot reaction of p -phthalaldehyde and 3-(diethylamino)phenol, which showed excellent selectivity, high sensitivity and a rapid response toward bisulfite in aqueous solution. Upon the addition of HSO3 −, the aldehyde moiety in probeRosCHO formed a hydrogen sulfite-dependent adduct product, leading to fluorescence enhancement due to the different ICT process. The detection limit for bisulfite was as low as 7 × 10 −8 M, and fluorescence imaging of bisulfite in MCF-7 cells demonstrated its value to practical application in biological systems.