Design of an amphiphilic porphyrin exhibiting high in vitro photocytotoxicity. (4th January 2016)
- Record Type:
- Journal Article
- Title:
- Design of an amphiphilic porphyrin exhibiting high in vitro photocytotoxicity. (4th January 2016)
- Main Title:
- Design of an amphiphilic porphyrin exhibiting high in vitro photocytotoxicity
- Authors:
- Topkaya, Derya
Lafont, Dominique
Poyer, Florent
Garcia, Guillaume
Albrieux, Florian
Maillard, Philippe
Bretonnière, Yann
Dumoulin, Fabienne - Abstract:
- Abstract : A promising photosensitiser, which exhibits extremely suitable properties for photodynamic applications is described. Abstract : A porphyrin monosubstituted by three triethyleneglycol chains grafted on a pentaerythritol skeleton was designed to display an optimized amphiphilicity for an enhanced cellular uptake and thus to exert enhanced photocytotoxicity. This porphyrin proved to be an excellent photosensitiser with submicromolar IC50 .
- Is Part Of:
- New journal of chemistry. Volume 40:Number 3(2016:Mar.)
- Journal:
- New journal of chemistry
- Issue:
- Volume 40:Number 3(2016:Mar.)
- Issue Display:
- Volume 40, Issue 3 (2016)
- Year:
- 2016
- Volume:
- 40
- Issue:
- 3
- Issue Sort Value:
- 2016-0040-0003-0000
- Page Start:
- 2044
- Page End:
- 2050
- Publication Date:
- 2016-01-04
- Subjects:
- Chemistry -- Periodicals
Chimie -- Périodiques
540 - Journal URLs:
- http://www.rsc.org/ ↗
http://www.rsc.org/is/journals/current/newjchem/njc.htm ↗ - DOI:
- 10.1039/c5nj02716k ↗
- Languages:
- English
- ISSNs:
- 1144-0546
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6084.319900
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 852.xml