A semi-interpenetrating network polyampholyte hydrogel simultaneously demonstrating remarkable toughness and antibacterial properties. (18th November 2016)

• Record Type: Journal Article
• Authors: Huang, Wei; Duan, Hongdong; Zhu, Liping; Li, Guoqiang; Ban, Qing; Lucia, Lucian A.
• Is Part Of: New journal of chemistry. Volume 40:Number 12(2016:Dec.)
• Page Start: 10520
• Page End: 10525
• Publication Date: 2016-11-18
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c6nj01833e
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : A hydrogel with toughness and antibacterial properties was prepared via interpenetrating CMCH with AM and MA while employing carboxylic–Fe 3+ . Abstract : Hydrogels have likely not made widespread penetration in biomedical engineering work due to several key hurdles such as poor mechanical strength and non-existent antimicrobial properties. A new semi-interpenetrating polymer network (Semi-IPN) hydrogel was prepared by interpenetrating carboxymethyl chitosan (CMCH) with acrylamide (AM) and maleic acid (MA) by covalent bond crosslinking enhanced by ionic (carboxylic–Fe 3+ ) secondary crosslinks. These hydrogels show a good tensile stress of about 1.44 MPa as well as outstanding antibacterial activity against Staphylococcus aureus and Gram-negative E. coli because of CMCH.