Efficacy of the MDM2 inhibitor SAR405838 in PDX models of GBM is limited by active efflux at the BBB. (December 2016) - Kim, M.; Gampa, G.; Laramy, J.; Zhang, S.; Ma, D.; Bakken, K.; Carlson, B.; Calligaris, D.; Agar, N.; Sarkaria, J.; Elmquist, W.