Base-promoted synthesis of 1H, 3H-pyrrolo[1, 2-c]thiazol-3-imine derivatives via [3+2] annulation of 2-alkynylpyrroles with isothiocyanates. Issue 47 (24th November 2016)
- Record Type:
- Journal Article
- Title:
- Base-promoted synthesis of 1H, 3H-pyrrolo[1, 2-c]thiazol-3-imine derivatives via [3+2] annulation of 2-alkynylpyrroles with isothiocyanates. Issue 47 (24th November 2016)
- Main Title:
- Base-promoted synthesis of 1H, 3H-pyrrolo[1, 2-c]thiazol-3-imine derivatives via [3+2] annulation of 2-alkynylpyrroles with isothiocyanates
- Authors:
- Zhang, Ziyin
Guo, Biao
Zhou, Yiming
Hua, Ruimao - Abstract:
- Abstract: Base-promoted [3+2] annulation of 2-alkynyl pyrrole with isothiocyanate affording 1 H, 3 H -pyrrolo[1, 2- c ]thiazol-3-imine derivatives has been developed. The control experiments suggest that the reaction proceeds via simple nucleophilic attack followed by intramolecular addition. The present cascade reaction provides a facile one-pot synthesis of 1 H, 3 H -pyrrolo[1, 2- c ]thiazol-3-imine derivatives under mild conditions with good yields and high regioselectivity. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 72:Issue 47(2016)
- Journal:
- Tetrahedron
- Issue:
- Volume 72:Issue 47(2016)
- Issue Display:
- Volume 72, Issue 47 (2016)
- Year:
- 2016
- Volume:
- 72
- Issue:
- 47
- Issue Sort Value:
- 2016-0072-0047-0000
- Page Start:
- 7613
- Page End:
- 7619
- Publication Date:
- 2016-11-24
- Subjects:
- 2-Alkynylpyrrole -- Annulation -- Isothiocyanate -- 1H, 3H-Pyrrolo[1, 2-c]thiazol-3-imine
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2016.10.017 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1171.xml