Engineering Protein Self‐Assembly: A New Approach for the Design of Octahedral Cages. (28th October 2016)

• Record Type: Journal Article
• Authors: Cougnon, Fabien B. L.
• Is Part Of: Chembiochem. Volume 17:Number 24(2016)
• Page Start: 2296
• Page End: 2298
• Publication Date: 2016-10-28
• Subjects: enzyme catalysis -- nanotechnology -- protein engineering -- self-assembly -- symmetry; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.201600526
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : A new symmetry‐based approach allowed the self‐assembly of an octahedral protein nanostructure. C 3 trimeric and C 4 tetrameric oligomerization domains can be combined in an engineered protein to direct assembly into a desired object. This work might provide the basis for a more general and flexible strategy to control protein self‐assembly.