Isolation of multiantennary N-glycans from glycoproteins for hepatocyte specific targeting via the asialoglycoprotein receptor. Issue 100 (12th October 2016)
- Record Type:
- Journal Article
- Title:
- Isolation of multiantennary N-glycans from glycoproteins for hepatocyte specific targeting via the asialoglycoprotein receptor. Issue 100 (12th October 2016)
- Main Title:
- Isolation of multiantennary N-glycans from glycoproteins for hepatocyte specific targeting via the asialoglycoprotein receptor
- Authors:
- Witzigmann, Dominik
Detampel, Pascal
Porta, Fabiola
Huwyler, Jörg - Abstract:
- Abstract : The asialoglycoprotein receptor (ASGPR) expressed on parenchymal liver cells specifically binds multivalent carbohydrates from desialylated glycoproteins. Abstract : The asialoglycoprotein receptor (ASGPR) expressed on parenchymal liver cells specifically binds multivalent carbohydrates from desialylated glycoproteins. This feature offers a huge potential for hepatocyte specific drug targeting. In this study, multiantennary N -glycans from asialofetuin have been isolated to actively target the asialoglycoprotein receptor on human hepatocellular carcinoma cells in vitro .
- Is Part Of:
- RSC advances. Volume 6:Issue 100(2016)
- Journal:
- RSC advances
- Issue:
- Volume 6:Issue 100(2016)
- Issue Display:
- Volume 6, Issue 100 (2016)
- Year:
- 2016
- Volume:
- 6
- Issue:
- 100
- Issue Sort Value:
- 2016-0006-0100-0000
- Page Start:
- 97636
- Page End:
- 97640
- Publication Date:
- 2016-10-12
- Subjects:
- Chemistry -- Periodicals
540.5 - Journal URLs:
- http://pubs.rsc.org/en/Journals/JournalIssues/RA ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6ra18297f ↗
- Languages:
- English
- ISSNs:
- 2046-2069
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8036.750300
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1811.xml