Phomeketales A–F, six unique metabolites from the endophytic fungus Phoma sp. YN02-P-3. Issue 69 (8th July 2016)

• Record Type: Journal Article
• Authors: Sang, Xia-Nan; Chen, Shao-Fei; Chen, Gang; An, Xiao; Li, Sheng-Ge; Li, Xiao-Ni; Lin, Bin; Bai, Jiao; Wang, Hai-Feng; Pei, Yue-Hu
• Is Part Of: RSC advances. Volume 6:Issue 69(2016)
• Page Start: 64890
• Page End: 64894
• Publication Date: 2016-07-08
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra12509c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Phomeketales A–F (1–6 ), six new xyloketals, with unprecendented carbon substitution at C-16 and C-17 simultaneously, were isolated from the endophytic fungus Phoma sp. YN02-P-3. Abstract : Phomeketales A–F (1–6 ), six new xyloketals, with unprecendented carbon substitution at C-16 and C-17 simultaneously, were isolated from the endophytic fungus Phoma sp. YN02-P-3. Their structures were elucidated on the basis of 1D and 2D NMR spectral data and ECD analysis. Compound 3 exhibited moderate anti-AChE activity and cytotoxicity against HL-60.