Crosslinking catalysis-active center of hemin on the protein scaffold toward peroxidase mimic with powerful catalysis. Issue 53 (13th May 2016)

• Record Type: Journal Article
• Authors: Dong, Minmin; Zhang, Liyan; Li, Rui; Li, Shuying; Jiang, Yao; Qiao, Yuchun; Duan, Zhiqiang; Li, Ru; Wang, Quanfu; Wang, Hua
• Is Part Of: RSC advances. Volume 6:Issue 53(2016)
• Page Start: 47595
• Page End: 47599
• Publication Date: 2016-05-13
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra07139b
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Catalytic hemin (Hem) was cross-linked onto the protein scaffold of bovine serum albumin (BSA) forming a Hem–BSA composite with powerful catalysis. Abstract : An enzyme mimic synthesis protocol has been proposed by simply cross-linking the redox active center of peroxidase onto a protein scaffold. Colorimetric assays and kinetic studies indicate that the developed peroxidase mimic can present much stronger catalysis and better aqueous stability than native hemin.