A three-dimensional graphene oxide supramolecular hydrogel for infrared light-responsive cascade release of two anticancer drugs. Issue 100 (25th November 2016)

• Record Type: Journal Article
• Authors: Ha, Wei; Zhao, Xiao-Bo; Jiang, Kan; Kang, Yang; Chen, Juan; Li, Bang-Jing; Shi, Yan-Ping
• Is Part Of: Chemical communications. Volume 52:Issue 100(2016)
• Page Start: 14384
• Page End: 14387
• Publication Date: 2016-11-25
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc08123a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A graphene oxide hybrid supramolecular hydrogel with a well-defined interior microstructure was developed for near infrared light-triggered cascade release of two anticancer drugs. Abstract : A three dimensional supramolecular hydrogel consisting of prodrug-modified graphene oxide and α-cyclodextrin was developed. This hydrogel with a well-ordered interior microstructure integrated hydrophobic and hydrophilic anticancer drugs into a single multifunctional platform, and underwent a gel–sol transition leading to cascade release of two drugs in an on-demand fashion upon NIR light irradiation.