Remote meta C–H bond functionalization of 2-phenethylsulphonic acid and 3-phenylpropanoic acid derivatives. Issue 96 (15th November 2016)

• Record Type: Journal Article
• Authors: Modak, Atanu; Mondal, Anirban; Watile, Rahul; Mukherjee, Semanti; Maiti, Debabrata
• Is Part Of: Chemical communications. Volume 52:Issue 96(2016)
• Page Start: 13916
• Page End: 13919
• Publication Date: 2016-11-15
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc08302a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : This discovery illustrates selective meta C–H bond activation from multiple non-equivalent C–H bonds present in medicinally relevant arylethanesulfonic acid and the 2-arylpropanoic acid moiety using weakly coordinating nitrile as a directing group. Abstract : This discovery illustrates selective meta C–H bond activation from multiple non-equivalent C–H bonds present in medicinally relevant arylethanesulfonic acid and the 2-arylpropanoic acid moiety using weakly coordinating nitrile as a directing group. Transformation of the meta olefinated compounds to important organic molecules has been demonstrated. Efforts were made to obtain mechanistic detail of the meta C–H bond functionalization reaction.