DNA based arithmetic function: a half adder based on DNA strand displacement. Issue 6 (27th January 2016)

• Record Type: Journal Article
• Authors: Li, Wei; Zhang, Fei; Yan, Hao; Liu, Yan
• Is Part Of: Nanoscale. Volume 8:Issue 6(2016)
• Page Start: 3775
• Page End: 3784
• Publication Date: 2016-01-27
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c5nr08497k
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : A half adder logic circuit based on DNA strand displacement reactions was designed and experimentally realized. The half adder is composed of an XOR gate and an AND gate, and it is a primary step toward constructing a full adder. Abstract : Biomolecular programming utilizes the reactions and information stored in biological molecules, such as proteins and nucleic acids, for computational purposes. DNA has proven itself an excellent candidate for building logic operating systems due to its highly predictable molecular behavior. In this work we designed and realized an XOR logic gate and an AND logic gate based on DNA strand displacement reactions. These logic gates utilize ssDNA as input and output signals. The XOR gate and the AND gate were used as building blocks for constructing a half adder logic circuit, which is a primary step in constructing a full adder, a basic arithmetic unit in computing. This work provides the field of DNA molecular programming with a potential universal arithmetic tool.