Technical pre‐analytical effects on the clinical biochemistry of Atlantic salmon (Salmo salar L.). Issue 1 (4th May 2016)

• Record Type: Journal Article
• Authors: Braceland, M; Houston, K; Ashby, A; Matthews, C; Haining, H; Rodger, H; Eckersall, P D
• Is Part Of: Journal of fish diseases. Volume 40:Issue 1(2017:Jan.)
• Page Start: 29
• Page End: 40
• Publication Date: 2016-05-04
• Subjects: clinical biochemistry -- diagnostics -- pre‐analytical -- reference range -- salmon -- Biochemistry -- Non‐destructive -- Health monitoring -- Pre‐analytical effects; Fishes -- Diseases -- Periodicals; 639.3
• DOI: 10.1111/jfd.12476
• Languages: English
• ISSNs: 0140-7775

Abstract

Abstract: Clinical biochemistry has long been utilized in human and veterinary medicine as a vital diagnostic tool, but despite occasional studies showing its usefulness in monitoring health status in Atlantic salmon ( Salmo salar L.), it has not yet been widely utilized within the aquaculture industry. This is due, in part, to a lack of an agreed protocol for collection and processing of blood prior to analysis. Moreover, while the analytical phase of clinical biochemistry is well controlled, there is a growing understanding that technical pre‐analytical variables can influence analyte concentrations or activities. In addition, post‐analytical interpretation of treatment effects is variable in the literature, thus making the true effect of sample treatment hard to evaluate. Therefore, a number of pre‐analytical treatments have been investigated to examine their effect on analyte concentrations and activities. In addition, reference ranges for salmon plasma biochemical analytes have been established to inform veterinary practitioners and the aquaculture industry of the importance of clinical biochemistry in health and disease monitoring. Furthermore, a standardized protocol for blood collection has been proposed.