A prototype system to measure X-ray absorption spectra for diagnosis in vivo. (November 2016)

• Record Type: Journal Article
• Authors: Hu, Bo; Zhang, Xingliang; Ouyang, Qinan; Wu, Xiaomei; Fang, Zheng
• Is Part Of: Measurement. Volume 93(2016)
• Page Start: 252
• Page End: 257
• Publication Date: 2016-11
• Subjects: X-ray absorption spectrum -- Diagnostic testing -- In vivo -- Radiation -- Prototype; Weights and measures -- Periodicals; Measurement -- Periodicals; Measurement; Weights and measures; Periodicals; 530.8
• DOI: 10.1016/j.measurement.2016.07.038
• Languages: English
• ISSNs: 0263-2241

Abstract

Abstract: We presented a new non-destructive test system for recording of X-ray absorption spectra. Its purpose was to investigate X-ray absorption spectral characteristics of organic and inorganic compounds and to explore the potential for biomedical pathological examination in vivo. An X-ray source with a maximum voltage of 80 kV and maximum current of 1 mA was selected for both good penetration and low radiation dose. A cadmium telluride (CdTe) detector was chosen for its wide energy range. Pulse-height analysis of the output of this sensor yielded energy spectra of X-rays that had passed through the sample. We calibrated the sensor with varying X-ray tube voltages and used tungsten X-ray lines to verify its accuracy. Different kinds of powders, aqueous solutions, aluminium alloys, and plastics were used as experimental samples to show their X-ray spectral absorption differences. The instrument had good prospects for further diagnostics combining radiology and tissue optics.