Identification and sequence analysis of two thaumatin‐like protein (TmTLP) genes from Tenebrio molitor. Issue 6 (11th October 2016)

• Record Type: Journal Article
• Authors: Noh, Mi Young; Jo, Yong Hun
• Is Part Of: Entomological research. Volume 46:Issue 6(2016:Nov.)
• Page Start: 354
• Page End: 359
• Publication Date: 2016-10-11
• Subjects: antimicrobial peptide -- in silico analysis -- Tenebrio molitor -- thaumatin‐like protein; Insects -- Korea -- Periodicals; Entomology -- Periodicals; 595.709519
• DOI: 10.1111/1748-5967.12198
• Languages: English
• ISSNs: 1738-2297

Abstract

Abstract: Thaumatin‐like proteins (TLPs) share structural similarity with the sweet‐tasting thaumatin protein but exhibit antifungal activity by inhibiting growth of fungal pathogens. In a Tenebrio model, two TLP genes were identified by RNA‐sequencing analysis and genome sequencing. Both TmTLP1 and TmTLP2 genes contain 729 nucleotide sequences encoding 242 amino acid residues, including an initiation codon (ATG) and a termination codon (TAA). Interestingly, TmTLP s are proteins with 14 central cysteine residues that may have an important role in structure formation. These data will be used to characterize the innate immune functions of TmTLPs in Tenebrio molitor .