Atypical psychotic symptoms and Dandy–Walker variant. Issue 5 (2nd September 2016)

• Record Type: Journal Article
• Authors: Williams, Aislinn J.; Wang, Zhenni; Taylor, Stephan F.
• Is Part Of: Neurocase. Volume 22:Issue 5(2016)
• Page Start: 472
• Page End: 475
• Publication Date: 2016-09-02
• Subjects: Schizophrenia -- psychosis -- cerebellum -- Dandy–Walker -- treatment resistant; Neurology -- Periodicals; Neuropsychology -- Case Report; Mental Disorders -- Case Report; Nervous System Diseases -- Case Report; 616.8
• DOI: 10.1080/13554794.2016.1237657
• Languages: English
• ISSNs: 1355-4794

Abstract

ABSTRACT: New-onset psychotic symptoms often respond well to antipsychotic treatment; however, symptoms may be difficult to treat when an underlying brain malformation is present. Here, we present a case of atypical psychotic symptoms in the context of a congenital cerebellar malformation (Dandy–Walker variant). The patient ultimately improved with paliperidone palmitate after multiple antipsychotic medication trials (both oral and one long-acting injectable) were ineffective. Neuroimaging may provide valuable diagnostic and prognostic information in cases of new-onset psychosis with atypical features and treatment resistance, even in the absence of neurologic signs and symptoms.