Multiplexed droplet Interface bilayer formation. Issue 24 (10th November 2016)

• Record Type: Journal Article
• Authors: Barlow, Nathan E.; Bolognesi, Guido; Flemming, Anthony J.; Brooks, Nicholas J.; Barter, Laura M. C.; Ces, Oscar
• Is Part Of: Lab on a chip. Volume 16:Issue 24(2016)
• Page Start: 4653
• Page End: 4657
• Publication Date: 2016-11-10
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/c6lc01011c
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : A movable PMMA device to reversibly form droplet interface bilayers (DIBs). Abstract : We present a simple method for the multiplexed formation of droplet interface bilayers (DIBs) using a mechanically operated linear acrylic chamber array. To demonstrate the functionality of the chip design, a lipid membrane permeability assay is performed. We show that multiple, symmetric DIBs can be created and separated using this robust low-cost approach.