A supramolecular fluorescent vesicle based on a coordinating aggregation induced emission amphiphile: insight into the role of electrical charge in cancer cell division. Issue 84 (3rd October 2016)

• Record Type: Journal Article
• Authors: Li, Jie; Shi, Kangjie; Drechsler, Markus; Tang, Ben Zhong; Huang, Jianbin; Yan, Yun
• Is Part Of: Chemical communications. Volume 52:Issue 84(2016)
• Page Start: 12466
• Page End: 12469
• Publication Date: 2016-10-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc06432a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Coordination of Zn 2+ triggers increased electrical charge of a fluorescent vesicle which further drives fission of the vesicle. Abstract : Binding of Zn 2+ to the coordinating supramolecular vesicle based on an aggregation induced emission amphiphile TPE-BPA immediately triggers the formation of charged vesicles. This induces vesicle fission and fluorescence reduction, suggesting a looser molecular packing in the charged vesicle membrane. Since cancer cells are highly charged, this indicates that the quick fission of cancer cells may have electrical charge origin.