Chemoselective reductive alkynylation of tertiary amides by Ir and Cu(i) bis-metal sequential catalysis. Issue 80 (19th September 2016)
- Record Type:
- Journal Article
- Title:
- Chemoselective reductive alkynylation of tertiary amides by Ir and Cu(i) bis-metal sequential catalysis. Issue 80 (19th September 2016)
- Main Title:
- Chemoselective reductive alkynylation of tertiary amides by Ir and Cu(i) bis-metal sequential catalysis
- Authors:
- Huang, Pei-Qiang
Ou, Wei
Han, Feng - Abstract:
- Abstract : We report a versatile method for the direct, catalytic reductive alkynylation of tertiary amides to give propargylic amines. Abstract : We report herein a convenient and versatile method for the direct reductive alkynylation of tertiary amides to give propargylic amines through sequential Ir-catalysed hydrosilylation–Cu(i )-catalysed alkynylation. The reactions proceed chemoselectively at the amide group in the presence of several sensitive functional groups including the very reactive aldehyde group on either the amide or the alkyne coupling partner. The method is general for tert -amides with or without α-hydrogen.
- Is Part Of:
- Chemical communications. Volume 52:Issue 80(2016)
- Journal:
- Chemical communications
- Issue:
- Volume 52:Issue 80(2016)
- Issue Display:
- Volume 52, Issue 80 (2016)
- Year:
- 2016
- Volume:
- 52
- Issue:
- 80
- Issue Sort Value:
- 2016-0052-0080-0000
- Page Start:
- 11967
- Page End:
- 11970
- Publication Date:
- 2016-09-19
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc05318a ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 26.xml