First description of herpes simplex virus type 1 epididymo-orchitis: A new clinical form of herpes simplex virus infection during septic shock?. (2016)

• Record Type: Journal Article
• Authors: Fromentin, Mélanie; Gauzit, Remy; Gille, Benoit; Samama, Charles Marc
• Is Part Of: IDCases. Volume 6(2016)
• Page Start: 26
• Page End: 28
• Publication Date: 2016
• Subjects: ICU intensive care unit -- CT computed tomography -- WOPN walled-off pancreatic necrosis -- PCR polymerase chain reaction -- ELISA enzyme linked immunosorbent assay -- SOFA sepsis-related organ failure assessment score; Septic shock -- Herpesviridae -- Epididymo-orchitis -- Necrotizing pancreatitis -- Immunosuppression -- Health care-associated infection; Communicable diseases -- Periodicals; Communicable Diseases -- Case Reports; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; 616.9
• DOI: 10.1016/j.idcr.2016.09.004
• Languages: English
• ISSNs: 2214-2509

Abstract

Abstract: Genital herpes is increasingly caused by herpes simplex virus type 1 (HSV-1), but recurrences are less frequent than with HSV-2. Distinguishing between primary genital infection and reactivation can be difficult, but HSV-1 more often causes severe primary infections and fewer recurrences. However, as virus reactivation is common during septic shock, a severe form of HSV-1 reactivation can occur in locations other than the lungs, which remain the most common site. The case of a 79-year-old Caucasian man who presented with HSV-1 epididymo-orchitis after three episodes of severe sepsis or septic shock in the context of acute biliary necrotizing pancreatitis is described. This is the first reported case of HSV-1 epididymo-orchitis due to virus reactivation during sepsis.