Effects of Prefracture Depressive Illness and Postfracture Depressive Symptoms on Physical Performance After Hip Fracture. Issue 11 (27th September 2016)

• Record Type: Journal Article
• Authors: Rathbun, Alan M.; Shardell, Michelle; Orwig, Denise; Gruber‐Baldini, Ann L.; Ostir, Glenn; Hicks, Gregory E.; Miller, Ram R.; Hochberg, Marc C.; Magaziner, Jay
• Is Part Of: Journal of the American Geriatrics Society. Volume 64:Issue 11(2016:Nov.)
• Page Start: e171
• Page End: e176
• Publication Date: 2016-09-27
• Subjects: hip fracture -- depression -- physical performance; Geriatrics -- Periodicals; 618.97
• DOI: 10.1111/jgs.14487
• Languages: English
• ISSNs: 0002-8614

Abstract

Abstract : Objectives: To compare the effect of prefracture depressive illness and postfracture depressive symptoms on changes in physical performance after hip fracture. Design: Longitudinal observational cohort. Setting: Baltimore metropolitan area. Participants: Older adults with hip fracture (N = 255). Measurements: Prefracture depressive illness (from medical records) at baseline and postfracture depressive symptoms at 2 months (using the Center for Epidemiologic Studies Depression Scale) were measured. Physical performance was measured 2, 6, and 12 months after fracture using the Short Physical Performance Battery (SPPB), a composite metric of functional status with a score ranging from 0 to 12. Weighted estimating equations were used to assess mean SPPB over time, comparing participants with and without prefracture depressive illness and subjects with and without postfracture depressive symptoms. Results: Participants with prefracture depressive illness had an SPPB increase of 0.4 units (95% confidence interval (CI) = −0.5–1.3) from 2 to 6 months, smaller than the increase of 1.0 SPPB unit (95% CI = 0.4–1.6) in those without prefracture depressive illness. Participants with postfracture depressive symptoms had an SPPB increase of 0.2 units (95% CI = −1.0–1.5) from 2 to 12 months, and those without postfracture depressive symptoms had a larger increase of 1.2 units (95% CI = 0.6–1.8) over the same period. Nevertheless, prefracture depressive illness and postfracture depressive symptoms were not significantly associated with SPPB. Conclusions: Neither prefracture depressive illness nor postfracture depressive symptoms were significantly associated with changes in physical performance after hip fracture, but the magnitude of estimates suggested possible clinically meaningful effects on functional recovery.