Molecularly imprinted polymer nanomaterials and nanocomposites by controlled/living radical polymerization. (November 2016)

• Record Type: Journal Article
• Authors: Beyazit, Selim; Tse Sum Bui, Bernadette; Haupt, Karsten; Gonzato, Carlo
• Is Part Of: Progress in polymer science. Volume 62(2016:Nov.)
• Page Start: 1
• Page End: 21
• Publication Date: 2016-11
• Subjects: 2, 4-D 2, 4-dichlorophenoxyacetic acid -- 4-VP 4-vinylpyridine -- AAm acrylamide -- AIBN azobisisobutyronitrile -- ATRA atom transfer radical addition -- ATRP atom transfer radical polymerization -- BDC benzyl diethyldithiocarbamate -- BET Brunauer–Emmett–Teller -- CNT carbon nanotube -- CRP controlled radical polymerization -- DEAEM diethylaminoethyl methacrylate -- DLS dynamic light scattering -- DSDMA bis(2-methacryloyloxyethyl) disulfide -- DVB divinylbenzene -- EGDMA ethylene glycol dimethacrylate -- FRP free radical polymerization -- GPC gel permeation chromatography -- HEMA 2-hydroxyethyl methacrylate -- MAA methacrylic acid -- MBAAm N, N′-methylene bis-acrylamide -- MIP molecularly imprinted polymer -- MMA methyl methacrylate -- NIP non-imprinted polymer -- NIPAM N-isopropylacrylamide -- NMP nitroxide-mediated radical polymerization -- PDI polydispersity index -- PEG200DMA polyethylene glycol 200 dimethacrylate -- PS polystyrene -- RAFT reversible addition fragmentation chain transfer -- S styrene -- SAM self-assembled monolayer -- SEM scanning electron microscopy -- SFRP stable free radical polymerization -- TED tetraethylthiuram disulfide -- Tg glass transition temperature -- TEM transmisson electron microscopy -- VBCl vinylbenzyl chloride; Molecularly imprinted polymer -- Controlled/living radical polymerization -- Nanocomposite -- Nanomaterial -- Surface functionalization; Polymers -- Periodicals; Polymerization -- Periodicals; Polymers -- Industrial applications -- Periodicals; Polymères -- Périodiques; Polymérisation -- Périodiques; 547.7
• DOI: 10.1016/j.progpolymsci.2016.04.001
• Languages: English
• ISSNs: 0079-6700

Abstract

Abstract: Since the pioneering work of Wulff and Mosbach more than 30 years ago, molecular imprinting of synthetic polymers has emerged as a robust and convenient way for synthesizing polymeric receptor materials bearing specific recognition sites for target molecules. The resulting materials, molecularly imprinted polymers (MIPs), are therefore commonly referred to as 'plastic antibodies'. They are obtained by polymerizing a scaffold around a target, or a derivate thereof, which acts as a molecular template. MIPs have been successfully applied in many areas including affinity separation, immunoassays, chemical sensing, solid-phase extraction, drug delivery, cell and tissue imaging, direct synthesis and catalysis. In terms of affinity and selectivity, MIPs are on a par with biological receptors like antibodies, and this is accompanied by a superior chemical and physical stability, compatibility with organic media, reusability, easy engineering and low cost. These advantages represent the main reasons for the wide interest raised around molecularly imprinted materials. Mainly produced by free radical polymerization (FRP) of vinyl monomers, MIPs have also taken advantage of the introduction of controlled/living radical polymerization (CRP) techniques, which have literally transformed polymer chemistry over the last decade. This review describes the advantages arising from the use of CRP in synthesizing MIPs, both in terms of sheer binding properties as well as for their remarkable potential for post-polymerization functionalization, for the synthesis of MIP nanomaterials and for the integration of MIPs into composites and hybrid materials. The benefits of using CRP are critically assessed with respect to the still largely applied FRP and guidelines are provided for choosing the most convenient technique to fit a specific targeted application of MIPs.