A new macrolactin antibiotic from deep sea-derived bacteria Bacillus subtilis B5. Issue 24 (16th December 2016)

• Record Type: Journal Article
• Authors: Li, Wei; Tang, Xi-Xiang; Yan, Xia; Wu, Zhen; Yi, Zhi-Wei; Fang, Mei-Juan; Su, Xin; Qiu, Ying-Kun
• Is Part Of: Natural product research. Volume 30:Issue 24(2016)
• Page Start: 2777
• Page End: 2782
• Publication Date: 2016-12-16
• Subjects: Bacillus subtilis B5 -- 7-O-2′E-butenoyl macrolactin A -- antifungal activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2016.1155576
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new macrolactin derivate, 7- O -2′ E -butenoyl macrolactin A (1 ), together with three known macrolactin compounds, macrolactin A (2 ), 7- O -malonyl macrolactin A (3 ) and 7- O -succinyl macrolactin A (4 ), was isolated from the bacterial strain Bacillus subtilis B5, which was isolated from the 3000 m deep sea sediment of the Southwest Pacific Ocean. The structures of the new compounds were assigned by spectroscopic methods including 1-D/2-D NMR and MS analysis techniques. Compounds1 and2 demonstrated antifungal activities against tea pathogenic fungi Pestalotiopsis theae and Colletotrichum gloeosporioides . Abstract :