Recurrent transient global amnesia as presenting symptoms of CADASIL. Issue 11 (28th September 2016)

• Record Type: Journal Article
• Authors: Pradotto, Luca; Orsi, Laura; Mencarelli, Monica; Caglio, Marcella; Lauro, Danilo; Milesi, Alessandra; Di Blasio, Anna; Mauro, Alessandro
• Is Part Of: Clinical case reports. Volume 4:Issue 11(2016)
• Page Start: 1045
• Page End: 1048
• Publication Date: 2016-09-28
• Subjects: CADASIL -- cognitive impairment -- dementia -- leukoaraiosis -- microbleeds -- NOTCH3 gene mutation -- transient global amnesia; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.666
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Despite transient global amnesia is considered unusual in Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and causal relation is still unclear, this report suggests to consider CADASIL in those patients with recurrent transient global amnesia, especially when MRI shows multifocal hyperintensities affecting the cerebral white matter or when it is followed by cognitive decline. Abstract : Despite transient global amnesia is considered unusual in Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and causal relation is still unclear, this report suggests to consider CADASIL in those patients with recurrent transient global amnesia, especially when MRI shows multifocal hyperintensities affecting the cerebral white matter or when it is followed by cognitive decline.