Two new sesquiterpenes from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities. Issue 22 (16th November 2016)

• Record Type: Journal Article
• Authors: Shen, Qinpeng; Xu, Xingmeng; Liu, Chunbo; Zhao, Wei; Xiang, Nengjun; Chen, Yongkuan; Miao, Mingming; Liu, Zhihua; Yang, Guangyu
• Is Part Of: Natural product research. Volume 30:Issue 22(2016)
• Page Start: 2545
• Page End: 2550
• Publication Date: 2016-11-16
• Subjects: Nicotiana tabacum -- sesquiterpenes -- anti-tobacco mosaic virus activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1120729
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new sesquiterpenes, nicotianasesterpenes A and B (1 and2 ), together with five known sesquiterpenes (3–7 ) were isolated from the leaves of Nicotiana tabacum . Their structures were determined mainly by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. The anti-tobacco mosaic virus (anti-TMV) activities of compounds1–7 were evaluated. The results revealed that compound1 exhibited high anti-TMV activities with inhibition rates of 33.6%. This rate is high than that of positive control. The other compounds also showed potential activities with inhibition rates in the range of 18.8–28.4%, respectively. Graphical abstract: The structures of compounds1 –2.