A straightforward green synthesis of N-(tert-butylsulfinyl)imines. Issue 10 (25th November 2016)

• Record Type: Journal Article
• Authors: Lv, Xirui; Zhou, Yue; Zhang, Anguo; Zhou, Lihong; Zeng, Qingle
• Is Part Of: Toxicological and environmental chemistry. Volume 98:Issue 10(2016)
• Page Start: 1155
• Page End: 1162
• Publication Date: 2016-11-25
• Subjects: N-(tert-butylsulfinyl)imines -- tert-butanesulfinamide -- aerobic oxidation -- green synthesis -- potassium tert-butoxide; Toxicology -- Periodicals; Environmental chemistry -- Periodicals; 571.95
• DOI: 10.1080/02772248.2015.1119834
• Languages: English
• ISSNs: 0277-2248

Abstract

Abstract : A straightforward and environment-friendly protocol for the synthesis of valuable chiral N -( tert -butylsulfinyl)imines has been developed. Different from traditional process with benzaldehydes as substrates, arylmethyl alcohols, benzylthiol, dibenzyl ether, thioether, and disulfide are used as alternative substrates to react with tert -butanesulfinamide in the presence of KO t Bu under air for the synthesis of chiral N -( tert -butylsulfinyl)imines. This is a transition metal-free, mild, cost-effective, and simple process.