Long-term outcomes of resection in patients with symptomatic benign liver tumours. Issue 11 (November 2016)

• Record Type: Journal Article
• Authors: van Rosmalen, Belle V.; Bieze, Matthanja; Besselink, Marc G.H.; Tanis, Pieter; Verheij, Joanne; Phoa, Saffire S.K.S.; Busch, Olivier; van Gulik, Thomas M.
• Is Part Of: HPB. Volume 18:Issue 11(2016)
• Page Start: 908
• Page End: 914
• Publication Date: 2016-11
• Subjects: Liver -- Diseases -- Periodicals; Biliary tract -- Diseases -- Periodicals; Pancreas -- Diseases -- Periodicals; 616.362005
• DOI: 10.1016/j.hpb.2016.07.013
• Languages: English
• ISSNs: 1365-182X

Abstract

Abstract: Background: Benign liver tumours (e.g., hepatocellular adenoma (HCA), focal nodular hyperplasia (FNH), and haemangioma) are occasionally resected for alleged symptoms, although data on long-term outcomes is lacking. The aim of this cross-sectional study was to assess long-term outcomes of surgical intervention. Methods: Forty patients with benign tumours (HCA 20, FNH 12, giant haemangioma 4, cysts 4) were included. Patients filled in Validated McGill Pain Questionnaires, preoperatively and after a median of 54 months after resection. Outcomes were evaluated using paired sample t-test and (M) ANOVA. Results: Relief of symptoms sustained in 30/40 patients, within a follow-up of 54 (24–148) months after resection. VAS scores were reduced from 5.5 preoperatively to 1.6 postoperatively ( p < 0.001). Patients with left-sided tumours had higher postoperative Pain Rating Index (PRI), compared to patients with right-sided tumours: 15.3 vs. 5.8 ( p = 0.018). If patients could reconsider undergoing surgery, 34/38 would again choose resection. Discomfort at the operative scar was the most common complaint: 8/40 patients, all after open surgery, of whom 3/40 had an incisional hernia. 7/40 patients had a laparoscopic resection. Conclusion: Resection relieved symptoms in 30/40 patients. The operative scar was a frequent source for remaining postoperative complaints, suggesting an advantage for a laparoscopic approach when feasible.