An examination of tissue engineered scaffolds in a bioreactor. Issue 1 (October 2016)

• Record Type: Journal Article
• Authors: Niedermeyer, Angela; Zhou, Bei; Dursun, Gözde; Stoffel, Marcus; Artmann, Aysegül; Markert, Bernd
• Is Part Of: Proceedings in applied mathematics and mechanics. Volume 16:Issue 1(2016)
• Page Start: 99
• Page End: 100
• Publication Date: 2016-10
• Subjects: Applied mathematics -- Periodicals; Engineering mathematics -- Periodicals; Mathematical physics -- Periodicals; 519
• DOI: 10.1002/pamm.201610038
• Languages: English
• ISSNs: 1617-7061

Abstract

Abstract: Replacement tissues, designed to fill in articular cartilage defects, should exhibit the same properties as the native material. The aim of this study is to foster the understanding of, firstly, the mechanical behavior of the material itself and, secondly, the influence of cultivation parameters on cell seeded implants as well as on cell migration into acellular implants. In this study, acellular cartilage replacement material is theoretically, numerically and experimentally investigated regarding its viscoelastic properties, where a phenomenological model for practical applications is developed. Furthermore, remodeling and cell migration are investigated. (© 2016 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)