Influence of Sonication on Morphological Properties of Poly(Vinyl Acetate) Particles Produced Through Suspension Polymerization. Issue 1 (October 2016)

• Record Type: Journal Article
• Authors: Azevedo, Gustavo D.; Melo, Príamo A.; Pinto, José Carlos
• Other Names: Pinto José Carlos guestEditor.; Balaban Rosangela guestEditor.
• Is Part Of: Macromolecular symposia. Volume 368:Issue 1(2016)
• Page Start: 78
• Page End: 83
• Publication Date: 2016-10
• Subjects: embolization -- poly(vinyl acetate) -- suspension polymerization -- ultrasound; Macromolecules -- Congresses; Polymers -- Congresses; Polymerization -- Congresses; Macromolecules -- Periodicals; Polymers -- Periodicals; Polymerization -- Periodicals; 547.705
• DOI: 10.1002/masy.201600024
• Languages: English
• ISSNs: 1022-1360

Abstract

Summary: The use of polymers for various medical purposes has increased significantly over the past few years, including vascular embolization procedures. The main challenge in this particular case is the development of embolic agents with suitable properties in order to render the application safer and reproducible. In this context, particle density plays a fundamental role in vascular embolization performance, since off‐spec values can lead to undesired sedimentation of particles during the medical procedure. The influence of sonication power on the morphology of polymer particles produced through suspension polymerizations was investigated in the present work, as well as the effects of adding polymer material into the initial monomer dispersion on the final morphological properties of the product. It is shown in particular that the investigated morphological properties (density, shape, porosity) depend on the operation conditions on manners that have not been discussed in the literature.