Chordomas and chondrosarcomas—The role of radiation therapy. Issue 5 (19th October 2016)

• Record Type: Journal Article
• Authors: De Amorim Bernstein, Karen; DeLaney, Thomas
• Is Part Of: Journal of surgical oncology. Volume 114:Issue 5(2016)
• Page Start: 564
• Page End: 569
• Publication Date: 2016-10-19
• Subjects: proton therapy -- rare tumors -- base of skull/spine; Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.24368
• Languages: English
• ISSNs: 0022-4790

Abstract

Abstract : Achieving negative surgical margins can be challenging for skull base and spinal/paraspinal sarcomas. Data shows that pre‐ or post‐operative radiation therapy improves local control. Delivery of sufficient dose of radiation can be difficult because of the proximity to normal organs/tissues that are sensitive to radiation therapy and therefore dose‐limiting. A comprehensive literature search was conducted using PubMed search engine. The scarcity of prospective, randomized data limits the ability to generate definitive treatment recommendations. J. Surg. Oncol. 2016;114:564–569 . © 2016 Wiley Periodicals, Inc.