Metabolic syndrome and periodontitis in Gullah African Americans with type 2 diabetes mellitus. (5th April 2013)

• Record Type: Journal Article
• Authors: Sora, Nicoleta D.; Marlow, Nicole M.; Bandyopadhyay, Dipankar; Leite, Renata S.; Slate, Elizabeth H.; Fernandes, Jyotika K.
• Is Part Of: Journal of clinical periodontology. Volume 40:Number 6(2013:Jun.)
• Page Start: 599
• Page End: 606
• Publication Date: 2013-04-05
• Subjects: diabetes mellitus -- Gullah population -- metabolic syndrome -- obesity -- periodontitis; Periodontics -- Periodicals; 617.6
• DOI: 10.1111/jcpe.12104
• Languages: English
• ISSNs: 0303-6979

Abstract

Abstract: Aim: To assess associations of metabolic syndrome, and its individual components, with extent of severe periodontitis among patients with type 2 diabetes mellitus (T2DM). Materials & Methods: We performed a secondary data analysis ( N = 283) using a cross‐sectional study population of Gullah African Americans with T2DM. Extent of severe periodontitis was assessed as total diseased tooth‐sites/person [evaluated as separate outcomes: 6+mm clinical attachment level (CAL), 5+mm periodontal probing depth (PPD)] using negative binomial regression techniques. Primary independent variables assessed in separate models included metabolic syndrome (yes/no), each metabolic syndrome component (low HDL, hypertension, high triglycerides, large waist circumference) and glycemic control (poor/good). Results: Multivariable CAL‐model results showed a significant association for metabolic syndrome status with extent of severe periodontitis (RR = 2.77, p = 0.03). The separate multivariable CAL‐model including each metabolic syndrome component showed marginally increased rates among those with large waist circumference (RR = 2.33, p = 0.09) and those with HbA1c ≥ 7% (RR = 1.73, p = 0.06). Multivariable PPD‐models showed marginally increased rates among those with metabolic syndrome (RR = 2.18, p = 0.06). Conclusion: Metabolic syndrome is associated with the extent of severe periodontitis in this Gullah population with T2DM.