Oxidative damage of naphthenic acids on the Eisenia fetida earthworm. Issue 11 (24th March 2015)

• Record Type: Journal Article
• Authors: Wang, Jie; Cao, Xiaofeng; Chai, Liwei; Liao, Jingqiu; Huang, Yi; Tang, Xiaoyan
• Is Part Of: Environmental toxicology. Volume 31:Issue 11(2016)
• Page Start: 1337
• Page End: 1343
• Publication Date: 2015-03-24
• Subjects: naphthenic acids -- oxidative stress -- genotoxicity -- antioxidant enzyme -- lipid peroxidation; Water quality bioassay -- Periodicals; Water -- Pollution -- Toxicology -- Periodicals; Microbiological assay -- Periodicals; Toxicity testing -- Periodicals; Environmental toxicology -- Periodicals; Environmental Pollution -- Periodicals; Environmental Pollutants -- Periodicals; Environmental Monitoring -- Periodicals; Écotoxicologie -- Périodiques; Pollution -- Périodiques; 615.902
• DOI: 10.1002/tox.22139
• Languages: English
• ISSNs: 1520-4081

Abstract

Abstract: Naphthenic acids (NAs) have been gaining recognition in recent years as potentially harmful environmental contaminants. Few studies have focused on the potential ecotoxicity of NAs to terrestrial environment. In this study, the responses of antioxidant system and lipid peroxidation and DNA damage were investigated after exposing Eisenia fetida to soil contaminated with NAs. The results indicated that NAs induced a significant increase ( p < 0.05) in superoxide dismutase and catalase enzyme activities. The glutathione peroxidase enzyme activities were significantly inhibited ( p < 0.05) in the medium and high dose treatments. An increase in malondialidehyde indicated that NAs could cause cellular lipid peroxidation in the tested earthworms. The percentage of DNA in the tail of comet assay of coelomocytes as an indication of DNA damage increased after treatment with different doses of NAs, and a dose‐dependent DNA damage of coelomocytes was found. In conclusion, oxidative stress caused by NAs exposure induces physiological responses and genotoxicity on earthworms. © 2015 Wiley Periodicals, Inc. Environ Toxicol 31: 1337–1343, 2016.