Two new 5‐deoxyflavan‐3, 4‐diol glucosides from roots of Albizia chevalieri. (6th September 2016)

• Record Type: Journal Article
• Authors: Tchoukoua, Abdou; Kuiate Tabopda, Turibio; Uesugi, Shota; Kimura, Ken‐ichi; Kwon, Eunsang; Momma, Hiroyuki; Ngadjui, Bonaventure Tchaleu; Koseki, Takuya; Shiono, Yoshihito
• Is Part Of: Magnetic resonance in chemistry. Volume 54:Number 11(2016:Nov.)
• Page Start: 893
• Page End: 896
• Publication Date: 2016-09-06
• Subjects: NMR -- 1H -- 13C -- Leguminosae -- Albizia chevalieri -- flavan‐3, 4‐diols -- cytotoxicity; Nuclear magnetic resonance spectroscopy -- Periodicals; Chemistry, Organic -- Periodicals; Magnetic resonance -- Periodicals; 538.36
• DOI: 10.1002/mrc.4504
• Languages: English
• ISSNs: 0749-1581

Abstract

Abstract: Phytochemical investigation of the roots of Albizia chevalieri led to the isolation of two new 5‐deoxyflavan‐3, 4‐diol glucosides from roots of A. chevalieri, Chevalieriflavanosides A and B. Their structures were established by 2D NMR techniques, UV, IR, CD, and mass spectrometry. Cytotoxicity of the two compounds was evaluated against acute promyelocytic leukemia HL60 cells. The antibacterial activities of 1 and 2 also were evaluated against Pseudomonas aeruginosa and Staphylococcus aureus using the agar diffusion test. Copyright © 2016 John Wiley & Sons, Ltd. Abstract : Two new 5‐deoxyflavan‐3, 4‐diol glucosides, Chevalieriflavanosides A (1 ) and B (2 ), were isolated from the roots of Albizia chevalieri . Their structures were established by 2D NMR techniques, UV, IR, CD, and mass spectrometry. Cytotoxicity and antibacterial activities of the two compounds were evaluated.