Simultaneous and interleaved acquisition of NMR signals from different nuclei with a clinical MRI scanner. Issue 5 (17th October 2016)

• Record Type: Journal Article
• Authors: Meyerspeer, Martin; Magill, Arthur W.; Kuehne, Andre; Gruetter, Rolf; Moser, Ewald; Schmid, Albrecht Ingo
• Is Part Of: Magnetic resonance in medicine. Volume 76:Issue 5(2016)
• Page Start: spcone
• Page End: spcone
• Publication Date: 2016-10-17
• Subjects: X‐nucleus -- interleaved -- simultaneous -- multinuclear -- MRS -- MRI; Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.26495
• Languages: English
• ISSNs: 0740-3194

Abstract

Abstract : Purpose: Modification of a clinical MRI scanner to enable simultaneous or rapid interleaved acquisition of signals from two different nuclei. Methods: A device was developed to modify the local oscillator signal fed to the receive channel(s) of an MRI console. This enables external modification of the frequency at which the receiver is sensitive and rapid switching between different frequencies. Use of the device was demonstrated with interleaved and simultaneous 31 P and 1 H spectroscopic acquisitions, and with interleaved 31 P and 1 H imaging. Results: Signal amplitudes and signal‐to‐noise ratios were found to be unchanged for the modified system, compared with data acquired with the MRI system in the standard configuration. Conclusion: Interleaved and simultaneous 1 H and 31 P signal acquisition was successfully demonstrated with a clinical MRI scanner, with only minor modification of the RF architecture. While demonstrated with 31 P, the modification is applicable to any detectable nucleus without further modification, enabling a wide range of simultaneous and interleaved experiments to be performed within a clinical setting. Magn Reson Med 76:1636–1641, 2016. © 2015 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.