Body distortions in Anorexia Nervosa: Evidence for changed processing of multisensory bodily signals. (30th November 2016)

• Record Type: Journal Article
• Authors: Zopf, Regine; Contini, Erika; Fowler, Chris; Mondraty, Naresh; Williams, Mark A.
• Is Part Of: Psychiatry research. Volume 245(2016)
• Page Start: 473
• Page End: 481
• Publication Date: 2016-11-30
• Subjects: Anorexia Nervosa -- Body perception -- Reaching -- Hand location -- Multisensory -- Proprioception -- Rubber hand illusion paradigm; Psychiatry -- Periodicals; Psychiatry -- periodicals; Psychiatrie -- Périodiques; 616.89
• DOI: 10.1016/j.psychres.2016.09.003
• Languages: English
• ISSNs: 0165-1781

Abstract

Abstract: Body size and shape distortion is a core feature of Anorexia Nervosa (AN) – patients experience their body as fat while objectively being very thin. The cause of this distortion is unclear and disturbances in body perception could be involved. Body perception comprises estimating shape and location of one's body and requires integrating multisensory signals. We investigated if and how body location perception is changed and tested 23 AN patients and 23 healthy controls (HC) in a Rubber Hand Illusion (RHI) reaching paradigm. We presented two types of multisensory conflicts (visual-proprioceptive hand location; visual-tactile touch synchrony) and tested if the impact of visual-proprioceptive and visual-tactile signals on hand location perception differs between AN and HC groups. We found significant group differences in shifts of reaching trajectories, indicating that the influence of proprioceptive signals on hand location estimates is reduced in AN. Hand location estimates were relatively more biased towards external visual information, and shorter illness durations predicted a larger visual bias. Although touch synchrony also significantly influenced hand location estimates, this effect did not differ between groups. Our findings provide compelling evidence that multisensory body location perception - specifically the processing of visual-proprioceptive signals – is changed in AN. Highlights: This is the first reaching study on multisensory body perception in Anorexia Nervosa. We used multisensory conflicts to study the influence of different sensory signals. For AN we found reduced impact of proprioceptive signals on hand location estimates. This provides compelling evidence that multisensory body perception is changed in AN. We suggest that bodily and/or neural alterations in AN change body signal processing.