A genotype–phenotype correlation study reveals that a non‐coding RNA might be associated with cardiovascular anomalies in fetuses with WHS. (19th August 2016)

• Record Type: Journal Article
• Authors: Wu, Yi; Tao, Jiong; Wang, Yan‐Lin; Hu, Wen‐Jing; Han, Xu; Cheng, Wei‐Wei
• Is Part Of: Prenatal diagnosis. Volume 36:Number 10(2016)
• Page Start: 979
• Page End: 981
• Publication Date: 2016-08-19
• Subjects: Prenatal diagnosis -- Periodicals; Fetus -- Diseases -- Diagnosis -- Periodicals; Electronic journals; 618.32075
• DOI: 10.1002/pd.4884
• Languages: English
• ISSNs: 0197-3851

Abstract

Abstract : What's Already Known About This Topic? Wolf–Hirschhorn syndrome is a genetic disorder caused by partial deletion of the short arm of chromosome It consists of a broad spectrum of clinical manifestations. The deletion size also varies significantly. What Does This Study Add? This study found that a non‐coding RNA (NR_130734) might be involved in cardiovascular development by analyzing the genotype–phenotype correlation of two fetuses with Wolf–Hirschhorn syndrome.