Go ahead, grow a head! A planarian's guide to anterior regeneration. Issue 3 (24th June 2016)
- Record Type:
- Journal Article
- Title:
- Go ahead, grow a head! A planarian's guide to anterior regeneration. Issue 3 (24th June 2016)
- Main Title:
- Go ahead, grow a head! A planarian's guide to anterior regeneration
- Authors:
- Owlarn, Suthira
Bartscherer, Kerstin - Abstract:
- Abstract: The unique ability of some planarian species to regenerate a head de novo, including a functional brain, provides an experimentally accessible system in which to study the mechanisms underlying regeneration. Here, we summarize the current knowledge on the key steps of planarian head regeneration (head‐versus‐tail decision, anterior pole formation and head patterning) and their molecular and cellular basis. Moreover, instructive properties of the anterior pole as a putative organizer and in coordinating anterior midline formation are discussed. Finally, we highlight that regeneration initiation occurs in a two‐step manner and hypothesize that wound‐induced and existing positional cues interact to detect tissue loss and together determine the appropriate regenerative outcomes.
- Is Part Of:
- Regeneration. Volume 3:Issue 3(2016)
- Journal:
- Regeneration
- Issue:
- Volume 3:Issue 3(2016)
- Issue Display:
- Volume 3, Issue 3 (2016)
- Year:
- 2016
- Volume:
- 3
- Issue:
- 3
- Issue Sort Value:
- 2016-0003-0003-0000
- Page Start:
- 139
- Page End:
- 155
- Publication Date:
- 2016-06-24
- Subjects:
- Organizer -- patterning -- planaria -- polarity -- regeneration -- Wnt -- wound
Regeneration (Biology) -- Periodicals
571.889 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2052-4412/ ↗
- DOI:
- 10.1002/reg2.56 ↗
- Languages:
- English
- ISSNs:
- 2052-4412
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 436.xml