Electrospun fibers of poly(butylene succinate–co–dilinoleic succinate) and its blend with poly(glycerol sebacate) for soft tissue engineering applications. (August 2016)

• Record Type: Journal Article
• Authors: Liverani, Liliana; Piegat, Agnieszka; Niemczyk, Agata; El Fray, Miroslawa; Boccaccini, Aldo R.
• Is Part Of: European polymer journal. Volume 81(2016:Aug.)
• Page Start: 295
• Page End: 306
• Publication Date: 2016-08
• Subjects: Electrospinning -- Poly(glycerol sebacate) -- Poly(butylene succinate-dilinoleic succinate) -- Soft tissue engineering; Polymers -- Periodicals; Polymerization -- Periodicals; Polymères -- Périodiques; Polymérisation -- Périodiques; Polymerization; Polymers; Periodicals; Electronic journals; 547.705
• DOI: 10.1016/j.eurpolymj.2016.06.009
• Languages: English
• ISSNs: 0014-3057

Abstract

Graphical abstract: Highlights: Synthesis of new copolymer poly(butylene succinate-dilinoleic succinate) has been obtained. Optimized electrospun fibers obtained for neat copolymer and blend with poly(glycerol sebacate). A feasibility study about blend spun fibers functionalization has been performed. Abstract: A new copolymer poly(butylene succinate-dilinoleic succinate) (PBS-DLS) has been successfully synthesized and its suitability for the fabrication of electrospun fiber mats has been investigated for the obtaining both electrospun scaffolds of neat PBS-DLS and also in blend with poly(glycerol sebacate) (PGS). After optimizing the electrospinning process for both neat and PGS/PBS-DLS (ratio 1:2) blend materials, homogeneous fiber mats have been obtained with an average fiber diameter of 2.5 ± 0.5 μm and 2.0 ± 0.2 μm, for neat and blend mats, respectively. Mechanical properties and degradation behavior in PBS were investigated to evaluate their suitability for soft tissue engineering applications. A feasibility study of the obtained electrospun mats functionalization was performed and positive results were obtained, demonstrating the versatility and suitability of PGS/PBS-DLS electrospun fibers as candidate for soft tissue engineering applications.